Chylothorax and chylous ascites due to juvenile paracoccidioidomycosis: a case report.

Paracoccidioidomycosis (PCM) is a systemic fungal infection caused by Paracoccidioides species. Chylothorax is a rare complication of PCM. A 16-year-old adolescent presented daily fever, lymphadenomegaly, sweating, weight loss, ventilatory-dependent pain, and dysphagia, which confirmed PCM. During treatment, the patient developed chylothorax and chylous ascites. Chronic inflammatory and fibrotic lymphadenopathy may obstruct lymphatic vessels, resulting in the extravasation of lymph into the abdomen or pleural cavities. Chylothorax is one of several complications of PCM and can lead to respiratory insufficiency, even in patients undergoing antifungal therapy.

Chylothorax and chylous ascites due to juvenile paracoccidioidomycosis: a case report

ABSTRACT Paracoccidioidomycosis (PCM) is a systemic fungal infection caused by Paracoccidioides species. Chylothorax is a rare complication of PCM. A 16-year-old adolescent presented daily fever, lymphadenomegaly, sweating, weight loss, ventilatory-dependent pain, and dysphagia, which confirmed PCM. During treatment, the patient developed chylothorax and chylous ascites. Chronic inflammatory and fibrotic lymphadenopathy may obstruct lymphatic vessels, resulting in the extravasation of lymph into the abdomen or pleural cavities. Chylothorax is one of several complications of PCM and can lead to respiratory insufficiency, even in patients undergoing antifungal therapy.

Whipple disease without joint involvement in a patient with chronic diarrhea and HIV seropositive partner: case report / Doença de Whipple sem envolvimento articular em paciente com diarréia crônica e parceira HIV-soropositiva: Relato de caso

Introduction: Whipple's disease is a rare, infectious disease caused by the bacterium Tropheryma whipplei that affects multiple organs and systems. It is difficult to identifyand frequently presents as a diagnosis of exclusion due existence of conditions causing most prevalent chronic diarrhea, as AIDS and Inflammatory Bowel Disease. Case report: Herein we report the clinical findings of a 38-year-old male patient, married with a HIV seropositive woman, with a four-year course of chronic diarrhea until he received a definitive diagnosis. Treatment was started with a 15-day penicillin G regimen, followed by continued trimethoprim­sulfamethoxazole 80/400mg after hospital discharge up to current days. Conclusion: Currently, the patient remains asymptomatic and has completed clinical remission after two years of treatment. (AU)

Introdução: A doença de Whipple é uma doença infecciosa rara causada pela bactéria Tropheryma whipplei que afeta múltiplos órgãos e sistemas. É difícil de identificar e freqüentemente se apresenta como um diagnóstico de exclusão devido à existência de condições que causam diarréia crônica mais prevalentes, como AIDS e Doença Infçamatória Intestinal. Relato do Caso: Aqui, relatamos os achados clínicos de um paciente do sexo masculino de 38 anos, casado com uma mulher HIV-soropositiva, com um curso de quatro anos de diarréia crônica até receber o diagnóstico definitivo. O tratamento foi iniciado com penicilina G por 15 dias, seguido de sulfametoxazol- trimetoprim 400/80 mg após a alta hospitalar até os dias atuais. Conclusão: Atualmente, o paciente permanece assintomático e apresentado remissão clínica completa após dois anos de tratamento. (AU)